Speciation of candida species isolated from patients with esophageal candidiasis and their antifungal susceptibility test to fluconazole

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Original Article

Author Details : Mohammad Zulfiqar Ali, Shweta R Sharma*, Amit Mishra, Umar Farooq, Sudhir Singh, Vasundhara Sharma, Imran Ahamad

Volume : 8, Issue : 1, Year : 2022

Article Page : 46-50

https://doi.org/10.18231/j.ijmmtd.2022.010

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Abstract

Context: Esophageal candidiasis is often observed in patients for its development and fluconazole is the therapeutic choice for the treatment.
Aim & Objectives: To determine its frequency, by performing upper gastrointestinal endoscopy and the frequency of various species isolated from patients with EC. To determine the antifungal susceptibility to fluconazole of isolated various species.
From January2020 to December 2020, total 73 patients found eligible for this study from endoscopy unit in Teerthanker Mahaveer medical hospital and research center (Moradabad), who presented whitish plaques consistent with esophageal candidiasis in order to identify species and verify their susceptibility to fluconazole.
Materials and Methods: Total 4256patients referred to UGI endoscopy at the endoscopy unit, 73(1.7%) had found esophageal candidiasis. Most affected age group from this disease was found 41-60 years (48%). Frequent number of species isolated was 50(68.5%). A total of 15(20.6%) isolated species were resistant to fluconazole, while 2(2.7%) had intermediate sensitivity to this drug.
Conclusion: Esophageal candidiasis prevalence was low although similar or within the results described by other authors. The common causative species was found for this disease and the resistant to fluconazole were considered high.
 
Keywords: Candida, Esophageal candidiasis, Antifungal susceptibility

How to cite : Ali M Z, Sharma S R, Mishra A, Farooq U, Singh S, Sharma V, Ahamad I, Speciation of candida species isolated from patients with esophageal candidiasis and their antifungal susceptibility test to fluconazole. IP Int J Med Microbiol Trop Dis 2022;8(1):46-50

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