Isolation & study of multidrug resistant Acinetobacter from various clinical samples in a tertiary care hospital

---

Original Article

Author Details : S.V. Wankhede, D.P. Ghadage, T.R. Patil, A.V. Bhore

Volume : 2, Issue : 2, Year : 2016

Article Page : 56-59

Suggest article by email

Get Permission

---

Abstract

Introduction: Nosocomial infections with Acinetobacter are being increasingly reported worldwide from debilitated& Critical care patients. Multidrug resistance among Acinetobacter are now a major cause of concern.
So the study was conducted to know prevalence & antimicrobial resistance pattern of Acinetobacter species in our area.
Materials & Methods: A total of 100 non-duplicate clinical specimens were processed for Acinetobacter by the routine microbiological procedures. Antimicrobial susceptibility testing was performed as per CLSI guidelines.
Result: Acinetobacter species were isolated from 9% of clinical samples. The higher percentage of isolates were from Pus 7(20%) followed by urine 1(4%) and 1(3%) from Blood. We found Highest isolates were from ICU -7(77.78%) followed by wards 2(22.22%). No isolates were found from Outpatient (OPD).
77% of our isolates showed resistance to drugs piperacillin-tazobactam and ceftriaxone while lower resistance was noted to ciprofloxacin &tetracyclines (33% respectively).
Resistance pattern for other drugs was co-trimaxazole (66%), gentamycin & piperacillin (55% respectively), amikacin, ofloxacin & imepenem - 44%. Interesting finding in our study was 11% of our isolated were sensitive to all the tested antimicrobials whereas 22% isolates were resistant to all the tested antimicrobials.
Conclusion: 22% of our isolates showed resistant to all the tested antimicrobials. Thus judicial use of antimicrobials & adopting strict infection control policies will be useful.

Key words: Multidrug resistance, Morbidity & Mortality, Acinetobacterspp, ICU & debilitated patients, Antimicrobial policy, Infection control

How to cite : Wankhede S, Ghadage D, Patil T, Bhore A, Isolation & study of multidrug resistant Acinetobacter from various clinical samples in a tertiary care hospital. IP Int J Med Microbiol Trop Dis 2016;2(2):56-59

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.