Bacteriological profile of surgical site infections and their antimicrobial susceptibility pattern at a tertiary care hospital, Western Gujarat

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Original Article

Author Details : Liyancy Prakash Patel, Hitesh K. Shingala, Krunal D Mehta*

Volume : 10, Issue : 2, Year : 2024

Article Page : 174-181

https://doi.org/10.18231/j.ijmmtd.2024.031

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Abstract

Background: Surgical site infection (SSI) is a frequently occurring repercussion of surgery. It results in mortality and morbidity post-surgery. The present study aims to isolate the organisms causing SSI and determine the antimicrobial susceptibility patterns of the isolates.
Materials and Methods: A total of 250 patient samples were included in the study, their demographic details obtained and processed as per Standard Microbiological Protocols. Antibiotic susceptibity of the positive cultures was performed using Modified Kirby-Bauer disc diffusion method.
Results: Out of the 250 samples, 102 (40.8%) samples showed positive culture growth. Positivity rates were higher in male patients (43.88%). The most prevalent Gram-negative isolate was Klebsiella pneumonia (23.53 %), followed by Escherichia coli (20.59%) and others. The only Gram-positive isolate was Staphylococcus aureus (21.57%). Most of the Gram-negative isolates were sensitive to imipenem, meropenem, ertapenem, ceftazidime-avibactam and aztreonam. Most of the gram-positive isolates were sensitive to linezolid and levofloxacin.
Conclusion: The current analysis found that Klebsiella pneumoniae was the most often related bacteria to SSI, followed by Staphylococcus aureus, Escherichia coli, and other infections. Periodic analysis of the causative organisms and their antimicrobial susceptibility pattern is necessary to confine the burden of SSI

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Keywords: Surgical site infection, Antimicrobial susceptibility, Gram­negative isolates, Staphylococcus aureus

How to cite : Patel L P, Shingala H K, Mehta K D, Bacteriological profile of surgical site infections and their antimicrobial susceptibility pattern at a tertiary care hospital, Western Gujarat. IP Int J Med Microbiol Trop Dis 2024;10(2):174-181

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