Dipodascus capitatus: A rare and emerging yeast like fungal infection in immuno-compromised subjects

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Original Article

Author Details : Degati Vijaya Lakshmi*, Battala Venkata Siva Prasad, Durbaka Vijaya Rahava Prasad

Volume : 9, Issue : 1, Year : 2023

Article Page : 17-25

https://doi.org/10.18231/j.ijmmtd.2023.004

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Abstract

Dipodascuscapitatus is a typical inhabitant of humans, especially on the skin, oral cavity, and respiratory tract. Fungi previously considered harmless colonizers (Opportunistic) are emerging as new fungal pathogens, particularly in an immune-compromised state. Infection caused by Dipodascuscapitatus is rare, and the treatment procedures are quite difficult. Here we reported the information on patients with chronic
diabetic conditions. The fungus was isolated from oral washings, the phenotypic identification was based on mycological methods, the molecular marker was based on 18S r RNA sequencing, and the susceptibility test was conducted by micro-dilution technique. The present study mainly focused on quantifying virulence factors, and their activity is expressed in the form of hemolysin protease (1.812 mg/ml). Fungal infections in these patients are often severe, rapid progressive, and challenging to identify, including diagnostic and therapeutic modalities required to provide better patient care.

Keywords: Non albicans Candida, Diabetics, Oral washings, Virulence factors, Drug resistance, Dipodascus capitatus

How to cite : Lakshmi D V, Prasad B V S, Prasad D V R, Dipodascus capitatus: A rare and emerging yeast like fungal infection in immuno-compromised subjects. IP Int J Med Microbiol Trop Dis 2023;9(1):17-25

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