IP International Journal of Medical Microbiology and Tropical Diseases

Official Publication of Khyati Education and Research Foundation


Volume 11, Issue 2, Year 2025
Editorial
Preparedness for communicable /infectious diseases outbreak in resource poor settings
Author details: Sarwat Fatima
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Original Article
Invitro studies on colon cancer cell inhibition by cell free extracts of natural probiotics and Bacillus clausii
Author details: Pranav Suresh Tambe, Ranjana Shirish Chavan, Shilpa Pranav Tambe, Gajanan Vishnu Mali
Background: Colorectal cancer (CRC) is an increasingly concerning health issue, which signifies in searching for new alternatives to minimize the side effects associated with chemotherapy and radiation therapy. Probiotic organisms belonging to genus Lactobacilllus and other genera and their derivati....
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Outbreak investigation of surgical site infections caused by Methicillin Resistant Staphylococcus aureus in patients undergoing total abdominal hysterectomy at tertiary care center
Author details: Vijeta Sharma, Swapnil Jain, Vijay Laxmi Sharma
Introduction: This report details surgical site infections (SSIs) due to Methicillin resistant staphylococcus aureus. SSIs was observed among patients undergoing Total abdominal hysterectomy procedures performed in between 15 days of time frame. Aim: The investigation aimed to identify the source of....
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Phenotypic detection of carbapenemase producing Pseudomonas aeruginosa isolated from clinical specimen in a tertiary care hospital
Aim and Objectives: The significant nosocomial pathogen Pseudomonas aeruginosa is inherently resistant to several medications. Metallo-beta-lactamases (MBLs) are a specific type of carbapenemase, belonging to class B enzymes. MBL producing Pseudomonas aeruginosa are a significant concern due to thei....
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Linezolid resistance among multidrug resistant tuberculosis isolates: Insights from North Karnataka, India
Author details: Tejashree A, Nivedita R Dhapalapu, Nirmala A, Rumana Begum N
Background: Drug-resistant tuberculosis (TB) is a serious threat to public health around the world. Treatment regimens have become more complex due to the growing number of reports of multidrug-resistant Mycobacterium tuberculosis (MDR-TB) worldwide. An increasing issue is the emergence of linezolid....
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Evaluation of multidrug resistant pathogens in wound infections: Bacteriological profiles and clinical outcome implication
Author details: Srilalitha Vishnubhatla, Satyanarayana Oruganti, Padmaja N
Background: One of the most common presentations in the outpatient department is pyogenic or wound infections. Multidrug-Resistant (MDR) bacterial infection is considered as one of the significant risk factor for impaired wound healing. The aim of this study is analysing bacteriological profiles and....
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Assessment of practices, menaces, and perception of the rural population of Alva Village in Gujarat towards brucellosis: A cross-sectional study to strengthen the "One Health" approach
Author details: Himani Bhardwaj Pandya, Nidhi Mihirkumar Bhalodia, Binda Prakashbhai Pipaliya, Saurabh Chhotalal Norris
Background: In Rural communities, A close relationship between People, livestock animals, and farming activities, along with poor medical services, makes them vulnerable to zoonotic infections. The rationale behind the study was to assess the practices, Risks, and attitudes of the rural people towar....
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Analysis of adenosine deaminase (ADA) Activity in HIV-positive individuals
Author details: Komal Waman Meshram, Arun Krishnarao Tadas, Poonam Lalla
Background & Objectives: Depletion of CD4+ T-lymphocytes is a hallmark of HIV infection. Therefore, CD4+ cell count is routinely done to monitor the progression of HIV infection. CD4+ cell count being costly could not be afforded everywhere in low-income countries. Thus, we aimed to ascertain the us....
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Analysis of clinical and laboratory profile of a recent dengue outbreak in a tertiary care hospital in Puducherry
Author details: Pon Roja Murugaraj, Shashikala Nair, Moses Marie Ambroise, Nimmy Elizabeth George
Background: Dengue fever is a mosquito-borne, self-limiting viral disease, endemic in tropical and subtropical regions around the world. Detection of NS1 antigen and IgM antibody are the basic methods for diagnosis. This study was done to analyze the demographic profile, association of serological m....
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Ribosomal protein S6: A Novel biomarker in the molecular era of breast cancer diagnosis and prognosis
Author details: Anmol Mahani, Viney Kumar, Vipul Nautiyal, Mansi Barthwal
Introduction: Carcinomas continue to be a significant global health challenge, with an estimated 20 million new cases and 9.7 million deaths reported world-wide, in 2022. In India, the carcinoma burden has been rising, with breast carcinoma being the leading cause of cancer incidence and mortality a....
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Unveiling the secrets of fowl adenovirus: A bioinformatics odyssey of phylogenetic analysis, structure prediction, ADMET analysis, molecular docking, and molecular dynamic simulation
Author details: Muhammad Danish Mehmood, Huma Anwar Ul-Haq, Faiza Khan, Abdul Rasheed Shaukat, Yasir Amin, Rabia Habib, Nusrat Tariq
Background: The project abstract outlines the significant genetic diversity and structural variability exhibited by Fowl Adenovirus (FAdV) isolates. 100 liver samples from suspected Adenovirus-infected bird samples underwent virus isolation through homogenization and filtration. Materials and Method....
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Assessment of hand hygiene compliance among healthcare workers at tertiary care hospital in Gujarat
Author details: Hiral K Patel, Jayasukhbhai D Mangukiya, Milankumar V Dharsandia, Payal D Soni, Vicky P Gandhi, Parimal H Patel
Background: Hand hygiene is a critical component of infection prevention and control in healthcare settings. This study aimed to assess hand hygiene compliance among healthcare workers (HCWs) at a tertiary care hospital in Gujarat. Materials and Methods: A cross-sectional observational study was con....
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Optimizing tuberculosis diagnosis: A comparative study of mycobacterial growth indicator tube (MGIT) versus GeneXpert for smear-negative pulmonary and extra-pulmonary cases
Author details: Kayalvili Kaliyamoorthy Sabha, Nivedhitha Elangovan, Arulselvan Subramanian, Selvi Elangovan
Background: Tuberculosis being a major global health issue. Accurate diagnosis of tuberculosis and drug resistance detection are the key components to manage Tuberculosis. Diagnosis in smear-negative pulmonary specimens & Extra-pulmonary specimens constitutes a major challenge. We studied the perfor....
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Detection of biofilm formation and their correlation with Imipenem resistance among clinical isolates of Pseudomonas aeruginosa
Author details: Vijetha Sajjanar, D E Premalatha
Background: Pseudomonas aeruginosa causes life threatening infections especially hospital acquired infections or nosocomial infections. Biofilm producing Pseudomonas aeruginosa isolates causes multidrug resistance pattern causing increase morbidity and mortality in a tertiary care hospital. Aim’s an....
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Trends of carbapenem resistance in Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacterales in a tertiary care hospital
Author details: Jagriti Bansal, Varun Goel, Nidhi Pal, Kushal Singh, Harmesh Manocha, Ajay Kumar Sahni
Introduction: Gram-negative pathogens resistant to carbapenems, including Acinetobacter baumannii, Pseudomonas aeruginosa and Carbapenem-resistant Enterobacterales (CRE) represent a significant public health threat. Enterobacterales are implicated in a wide range of medical infections, which pose si....
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Clinicomycological study on identification and antifungal susceptibility testing of dermatophytes at a tertiary care hospital in Tamil Nadu
Author details: Sumayya Fathima H, Sumetha Suga D, Kalpana Devi V, Ananthi B, Subha S
Background and Aim: The most prevalent cutaneous fungal infection is dermatophytosis, which is caused by a class of keratinophilic filamentous fungus known as dermatophytes. There is dramatic rise in recalcitrant and extensive dermatophytosis associated with antifungal resistance. So early and accur....
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Microbiological Profile and Risk Assessment of surgical- site infections following Obstetric and Gynecological Surgeries: A study at a rural-based tertiary care hospital
Author details: Nidhi Mihirkumar Bhalodia, Mihirkumar J Bhalodia, Himani Pandya, Tanuja Javadekar, Sucheta Lakhani
Introduction: Surgical site infections are the second most common cause of maternal mortality after postpartum hemorrhage in obstetrics and gynecology. Surgical site infections account for about 38% of health care-associated infections among patients admitted to the obstetrics and gynecology departm....
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Determining RPO Gene mutation responsible for rifampicin resistance in pulmonary tuberculosis assessed by line probe assay
Author details: Nidhi Singh, Ved Prakash Sharma, Amit Kumar Singh, Rajesh Agarwal, Rajesh Shah
Introduction: Mycobacterium tuberculosis causes TB illness, which is increasingly widespread. The Geno Type MTBD Rplus assay or line probe assay (LPA) detects the most prevalent genetic changes generating rifampicin (RIF) resistance at (rpoB gene mutations) codons 516, 526, and 531, as well as Mycob....
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Case Report
Primary pulmonary amoebiasis complicated with right-sided pneumothorax and multicystic empyema: A case report
Author details: Nidhi Mihirkumar Bhalodia, Mihirkumar J Bhalodia, Himani Pandya, Tanuja Javadekar, Sucheta Lakhani
Amoebiasis is the most common parasitic infection caused by the protozoan Entamoeba histolytica. Around 90% of the infections are asymptomatic, and in the majority of the cases, the common clinical manifestation is amoebic dysentery. The most common site of extraintestinal invasion is the liver, and....
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Case Series
Exploring adverse drug reactions in first-line antitubercular treatment: A case series
Author details: Pedada Mounika, Elen Ann Abraham, Ghanshyam Verma, Akhil Anand, Keerthana Priya
Managing adverse drug reactions (ADRs) remains a significant hurdle despite the high efficacy of standard anti-tuberculosis treatments. The majority of ADRs were classified as clinical (53%), predominantly occurring early in treatment (82.5%) and characterized as mild to moderate (88.7%), mainly fal....
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