A distinctive genomic feature, the spike gene S Gene Target Failure (SGTF), enables accurate detection of the Alpha and Omicron SARS-CoV-2 variants of Gujarat region.

Authors: NILAY HARSHADKUMAR DAVE, Neeraj Arora, Dr Chetana Roat

Keywords: SARS-Cov-2, STGF, Spike Gene Target Failure, Alpha, Omicron, Taqpath RT-PCR, Next Generation Sequencing, VOC

SARS-COV-2 is the infectious agent that causes COVID-19. Several mutations in the spike gene are shared by the Alpha (B.1.1.7) and Omicron (B.1.1.529, BA.1, BA.4, and BA.5) variants of concern (VOC)....

Culture and Sensitivity in Cancer Patients Presenting with Sepsis

Authors: Veena Boswal, Anmol Mahani, Luckshay Sharma, Vipul Nautiyal, Viney Kumar, Mansi Barthwal

Keywords: Cancer, Sepsis, Antibiotic Resistance, Culture and Sensitivity, Bacteraemia, Chemotherapy, Retrospective Study

Introduction: Introduction: Cancer management has significantly evolved over recent decades with the advancement of multimodal treatment strategies, including surgery, chemotherapy, immunotherapy, and...

Study of Candida Infections in Hospitalized COVID-19 Patients: An Experience at a Dedicated COVID Hospital in Central India

Authors: Aniket Goenka, Saurabh G Agarwal, Sanyogita Jain, Kuldeep Singh, Rajdeep Paul, Ajay Goenka

Keywords: Candida species, COVID-19, antifungal resistance, fluconazole, Candida albicans, Candida tropicalis, diabetes, hypertension, tertiary care hospital

Background: Candida infections have become increasingly common in patients with COVID-19, particularly in those with comorbidities or requiring prolonged hospital stays. The growing incidence of funga...

Phenotypic detection of β-lactamases producing Klebsiella pneumoniae and Acinetobacter baumannii isolated from the respiratory tract infections.

Authors: Shilpa Borehalli Mayegowda, Priyanka Lakshman, Sushma S Murthy, Manjula Nagalapur Gadilingappa

DOI: 10.18231/j.ijmmtd.11625.1758782202

Keywords: Antimicrobials, ESBL, MBL, Antibiotic susceptibility test, Colistin.

The limited treatment options have elevated an increased cause of concerns toward the emerging antimicrobial resistance amongst the bacterial pathogens in hospital settings, causing respiratory tract...

Concordance of Enterococcus species identification by two different identification systems VITEK2 and MALDI-TOF, compared with WGS (gold standard).

Authors: shital sangani, Anant Prabhakar Marathe, Bhavita Thakorbhai Prajapati, Asmabanu Mahammed Hanif Shaikh

DOI: 10.18231/j.ijmmtd.12016.1760520062

Keywords: Bloodstream infections,Enterococcus,MALDI-TOF,VITEK2,Whole Genome Sequencing

Abstract: Aims & Objective: This study aims to compare the performance of two commercial systems, VITEK2 and MALDI-TOF (Matrix-assisted laser desorption-ionization time-of-flight mass spectrometry), i...

An Unusual Case of Disseminated Hydatid Cyst of Liver, Spleen and Urinary bladder

Authors: Jigna P. Patel, Jaina A. Shah, Mansi D. Rupani

DOI: 10.18231/j.ijmmtd.11948.1759746971

Keywords: Cyst within cyst appearance, Hydatid cysts, Livestock-producing countries, Spoke in wheel appearance

Hydatid disease is a common health problem in endemic regions, particularly in livestock-producing countries. Humans acquire infestation of echinococcus by swallowing the ova accidentally. Infections...

Estradiol-Associated Shifts in Vaginal Microbiota: Insights from Menopausal and Reproductive Women

Authors: Siti Anissa Safira, Sharvianty Arifuddin, Fatmawati Madya, Andi Alfian Zainuddin, Sriwijaya Sriwijaya, Irma Savitri

DOI: 10.18231/j.ijmmtd.12107.1759749938

Keywords: estradiol, dysbiosis, menopause, microbiota

Background and Objective: Estradiol plays a key role in maintaining vaginal microbial balance, particularly by supporting Lactobacillus dominance. Hormonal shifts during menopause may disrupt this bal...

Comparison of in vitro activity of cefepime-enmetazobactam and other carbapenem-sparing agents for gram negative uropathogens

Authors: Kalaivani Ramakrishnan, Arunava Kali, Sarah Korah, Thouheedha Banu S, Srirangaraj Sreenivasan

DOI: 10.18231/j.ijmmtd.12708.1760517812

Keywords: Cefepime-enmetazobactam, Carbapenem-sparing antibiotic, Extended-Spectrum β-Lactamase, Multidrug-resistance

Background: Urinary tract infections (UTIs) caused by Gram-negative bacteria are an emerging therapeutic concern due to resistance to third-generation cephalosporins associated with Extended-spectrum...